Recursion Pharmaceuticals Achieves Breakthrough With Boltz-2 AI Model
$RXRX
In a significant advancement for the pharmaceutical industry, Recursion Pharmaceuticals (NASDAQ:RXRX) has recently unveiled its latest innovation, the Boltz-2 AI model, which is set to revolutionize the field of drug discovery. This cutting-edge model, developed in collaboration with the Massachusetts Institute of Technology (MIT), has demonstrated unprecedented speed, scale and accuracy in predicting binding affinity, a crucial factor in the development of new medications.
Boltz-2 stands out as the first biomolecular co-folding model that not only predicts molecular structure but also their interactions at an accuracy level comparable to the industry-standard physics-based free energy perturbation (FEP) calculations. However, what makes Boltz-2 evolutionary is its ability to perform these predictions up to 1,000 times faster than current methods. This enhancement is largely due to the utilization of Recursion’s NVIDIA-powered supercomputer, BioHive-2, which supports the model’s intensive computational demands.
By significantly reducing the time and cost associated with the early stages of drug discovery, Boltz-2 enables pharmaceutical companies to more effectively triage and prioritize compounds for development. This could lead to faster introduction of effective drugs into the market, addressing urgent medical needs more swiftly.
Najat Khan, Chief R&D Officer and Chief Commercial Officer at Recursion, emphasized the transformative potential of Boltz-2. According to Khan, “Selecting the right molecules early is one of the most fundamental challenges in drug discovery, with implications for whether R&D programs succeed or fail.” She further noted that Boltz-2 provides R&D teams with a powerful tool to more effectively focus their resources on the most promising compounds. The development of Boltz-2 is a prime example of successful collaboration between academia and industry.
Boltz-2 will be made available under an MIT license, allowing both academic and commercial entities to access and build upon this groundbreaking work. Recursion’s commitment to innovation extends beyond Boltz-2. The company is known for its Recursion OS platform, which integrates diverse technologies to generate one of the world’s largest proprietary biological and chemical datasets.
This platform enables the company to leverage sophisticated machine-learning algorithms, which distill trillions of searchable relationships across biology and chemistry, free from human bias. As Recursion continues to lead in the TechBio space, its efforts are set to have a lasting impact on the pharmaceutical industry and healthcare as a whole. By harnessing the power of AI and high-performance computing, The firm not only enhances its own drug development capabilities but also contributes to the broader goal of improving patient outcomes through more effective and efficiently developed therapies.
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